L-Ascorbic Acid 6-Hexadecanoate, also known as Ascorbyl Palmitate, is a derivative of Vitamin C (ascorbic acid). Its unique properties make it a versatile compound widely used in cosmetics, food preservation, and pharmaceuticals. This ultimate guide explores its structure, applications, benefits, and usage in detail.
1. What is L-Ascorbic Acid 6-Hexadecanoate?
L-Ascorbic Acid 6-Hexadecanoate is an ester formed by combining ascorbic acid with palmitic acid, a fatty acid. This combination makes it fat-soluble, unlike pure Vitamin C, which is water-soluble.
- Chemical Formula: C22H38O7
- Molecular Weight: 414.53 g/mol
- Appearance: White to off-white crystalline powder
- Solubility: Soluble in fats and oils, partially soluble in alcohols
2. Key Properties of L-Ascorbic Acid 6-Hexadecanoate
- Stability: More stable than pure Vitamin C, making it resistant to oxidation.
- Fat Solubility: Allows incorporation into oil-based products.
- Antioxidant Power: Retains Vitamin C's ability to neutralize free radicals.
3. Applications
3.1. Cosmetics and Skincare
L-Ascorbic Acid 6-Hexadecanoate is a popular ingredient in skincare products due to its antioxidant and skin-brightening properties.
- Anti-aging: Reduces fine lines and wrinkles by stimulating collagen production.
- Brightening: Lightens hyperpigmentation and evens skin tone.
- UV Protection: Enhances the efficacy of sunscreens by neutralizing free radicals generated by UV rays.
3.2. Food Preservation
- Acts as an antioxidant to prevent oxidation of fats and oils in food products, extending shelf life.
- Commonly used in snacks, margarine, and instant noodles.
3.3. Pharmaceuticals
- Enhances stability in Vitamin C formulations for tablets, capsules, and topical applications.
- Potential applications in anti-inflammatory and immune-boosting products.
4. Benefits of L-Ascorbic Acid 6-Hexadecanoate
- Longer Shelf Life: Unlike pure Vitamin C, it remains effective over extended periods.
- Versatility: Can be used in both oil-based and water-based formulations.
- Improved Skin Penetration: Fat solubility allows better absorption in skin layers.
5. How to Use L-Ascorbic Acid 6-Hexadecanoate
For Skincare Formulations
- Concentration: Use at 1-10% depending on the formulation.
- Combination: Pairs well with Vitamin E and ferulic acid for enhanced stability and efficacy.
- Packaging: Store in air-tight, light-resistant containers to maintain potency.
For Food Applications
- Add to fats and oils during processing for antioxidant benefits.
6. Comparison with Pure Vitamin C (Ascorbic Acid)
| Property | L-Ascorbic Acid | L-Ascorbic Acid 6-Hexadecanoate |
|---|---|---|
| Solubility | Water-soluble | Fat-soluble |
| Stability | Low | High |
| Shelf Life | Short | Long |
| Skin Penetration | Moderate | Excellent |
| Applications | Limited | Versatile |
7. Safety and Precautions
- Safety Profile: Generally recognized as safe (GRAS) for use in foods and cosmetics.
- Allergic Reactions: Rare but may occur in sensitive individuals. Perform a patch test before use.
- Storage: Keep in a cool, dry place away from direct sunlight.
8. Where to Source L-Ascorbic Acid 6-Hexadecanoate
Look for reputable manufacturers and suppliers with certifications such as GMP, ISO, and FDA. Ensure product quality and consistency by requesting Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS).
Conclusion
L-Ascorbic Acid 6-Hexadecanoate is a versatile and potent derivative of Vitamin C, offering enhanced stability and expanded applications. From its role in skincare and food preservation to pharmaceutical innovations, its benefits are vast and impactful. Whether you’re formulating a cosmetic product or preserving food, this compound is a valuable addition to your toolkit.
